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中药制剂学

章津铭

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个人简介:

        章津铭,教授,现任必赢体育app下载,必赢体育药学院/现代中药产业学院副院长。主要研究方向为中药新型纳米递药系统及中医药健康产品开发。省部级优秀人才计划入选者、中国科协第四届青年人才托举工程人选、四川省杰出青年科技人才、四川省“特聘专家”、四川省中医药管理局学术技术带头人,荣获全国高等中医药院校优秀青年、四川省优秀党务工作者、四川省五四青年教师榜样等荣誉。承担国家自然科学基金面上项目基金、青年科学基金、中国博士后科学基金面上资助项目、中国博士后科学基金特别资助项目、四川省杰出青年科技人才项目等国家级、省部级等项目。以第一作者或通讯作者在Adv Drug Deliv Rev、Acta Pharm Sin B、Theranostics等学术期刊发表SCI论文100余篇,入选2020年度、2022年度“全球前2%顶尖科学家榜单”(药学领域)(H-index 35),获授权发明专利8项,参与编写教材及专著多部,担任Chin Chem Lett、Chin Med、iMeta等期刊青年编委,中华中医药学会第二届青年委员会委员、世中联中药新型给药系统专业委员会常务理事等。

部分代表性成果如下:

1. Quan Gao, Jiao Feng, Wencheng Liu, Chengyong Wen, Yihan Wu, Qian Liao, Liang Zou, Xinbing Sui, Tian Xie, Jinming Zhang*, Yichen Hu*. Opportunities and challenges for co-delivery nanomedicines based on combination of phytochemicals with chemotherapeutic drugs in cancer treatment[J]. Adv Drug Deliv Rev. 2022, 188: 114445.

2. Yihan Wu, Jiaxin Li, Liang Zou, Chaomei Fu, Meiwan Chen, Jinming Zhang*, Huile Gao. A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy[J]. Asian J Pharm Sci. 2022, 17(02): 206-218.

3. Qian Liao, Lan Pang, Jing-Jing Li, Chen Zhang, Jia-Xing Li, Xing Zhang, Ting Mao, Ding-Tao Wu, Xiu-Ying Ma, Fu-Neng Geng, Jin-Ming Zhang*. Characterization and diabetic wound healing benefits of protein-polysaccharide complexes isolated from an animal ethno-medicine Periplaneta americana L[J]. Int J Biol Macromol. 2022, 195: 466-474.

4. Jinfeng Shi#, Yali Ren#, Jiaqi Ma, Xi Luo, Jiaxin Li, Yihan Wu, Huan Gu, Chaomei Fu, Zhixing Cao*, Jinming Zhang*. Novel CD44-targeting and pH/redox-dual-stimuli-responsive core-shell nanoparticles loading triptolide combats breast cancer growth and lung metastasis[J]. J Nanobiotechnology. 2021, 19(01): 188.

5. Xiao Wang, Huan Gu, Huan Zhang, Jing Xian, Jingjing Li, Chaomei Fu, Chen Zhang, Jinming Zhang*. Oral Core-Shell Nanoparticles Embedded in Hydrogel Microspheres for the Efficient Site-Specific Delivery of Magnolol and Enhanced Antiulcerative Colitis Therapy[J]. ACS Appl Mater Interfaces. 2021, 13(29): 33948-33961.

6. Liang Zou , Xiaowei Liu, Jingjing Li, Wei Li, Lele Zhang, Chaomei Fu, Jinming Zhang?, Zhongwei Gu?. Redox-sensitive carrier-free nanoparticles self-assembled by disulfide-linked paclitaxel-tetramethylpyrazine conjugate for combination cancer chemotherapy [J]. Theranostics, 2021, 11(09): 4171.

7. Yaoyao Luo#, Jingjing Li#, Yichen Hu, Fei Gao, George Pak-Heng Leung, Funeng Geng, Chaomei Fu*, Jinming Zhang*. Injectable thermo-responsive nano-hydrogel loading triptolide for the anti-breast cancer enhancement via localized treatment based on “two strikes” effects[J]. Acta Pharm Sin B, 2020, 10(11): 2227-2245.

8. Xiaoqin Yang, Yihan Wu, Chen Zhang, Shu Fu, Jinming Zhang*, Fu Chaomei*. Extraction, structural characterization, and immunoregulatory effect of a polysaccharide fraction from Radix Aconiti Lateralis Preparata (Fuzi)[J]. Int J Biol Macromol, 2020, 143: 314-324.

9. Jingjing Li#, Yihan Wu#, Di Wang, Liang Zou, Chaomei Fu, Jinming Zhang*, Leung George Pak-Heng*. Oridonin synergistically enhances the anti-tumor efficacy of doxorubicin against aggressive breast cancer via pro-apoptotic and anti-angiogenic effects[J]. Pharmacol Res, 2019, 146: 104313.

10. Jinming Zhang, Jingjing Li, Zhi Shi, Yang Yang, Xi Xie, Simon MingYuen Lee*, Yitao Wang, Kam W Leong, Meiwan Chen*. pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities[J]. Acta Biomaterialia, 2017, 58: 349-364.