黄林芳
一、个人简介
黄林芳研究员,中国医学科学院药用植物研究所鉴定中心,研究员,博士生导师,日本京都大学博士后。2024、2023、2022年“中国高被引学者”,2022年全球前2%顶尖科学家“年度影响力”。
“中药品质生态学”新兴交叉学科的主要创立者。研究领域为(1)中药资源;(2)中药鉴定;(3)中药质量评价。研究方向为(1)“中药品质生态学”的道地药材创新研究;(2)种植环境优化与清洁生产的中药材品质提升关键技术研发;(3)面向临床的中药新药发现与健康产品研发。
国家重大新药创制、科技部、NSFC评审专家,教育部“长江学者和创新团队发展计划”学术骨干,北京协和医学院优秀教师。药用植物研究所学术委员会、学位委员会及教育教学委员会委员。在中药品质生态创新理论与实践研究中做出突出贡献。获学术奖励5项(含行业学会科技进步二等奖2项-第1,三等奖1项-第1;省部级科技进步二等奖1项),以第一或通讯作者发表论文 200余篇(含中科院一区top期刊科学通报、中国科学、J CLEAN PROD(IF=11.1)等,SCI百余篇),编写著作31部(主编、副主编7部),获授权专利30件(美国专利1件)。主持项目30余项(国家自然基金 6 项,北京市自然基金 2 项)。培养硕博研究生 50余人。8人次获硕博国家奖学金,协和学生14人全部获得奖学金,多人获得北京协和医学院学业奖学金、北京协和医学院优秀毕业生,药植所博硕士科研排名第一科研奖及药植所 Top10 奖学金。
邮箱:15801545922@139.com, lfhuang@implad.ac.cn
二、代表性成果(可含承担项目、发表论文、论著、获奖等)
(一)承担项目
1. 国家自然基金面上项目:肉苁蓉及盐生肉苁蓉分类修订及品质评价(项目编号82274045)
2. 国家自然基金面上项目:异质生境肉苁蓉与梭梭协同适应机理研究(项目编号82073960)
3. 国家自然基金面上项目:地理格局及生态驱动揭示肉苁蓉品质生态型机理(项目编号81473315)
4. 国家自然基金国际合作项目:中巴传统食药品种肉苁蓉基原物种及寄主植物鉴定余安全性研究(项目编号822110453)
5. 国家自然基金面上项目:西洋参不同产地品质相关“地理特异性基因群”的发掘(项目编号)81274013
6. 北京市自然科学基金面上项目:北京地区产西洋参品质形成及机制研究(项目编号7202135)
7. 北京市自然科学基金面上项目:西洋参品质形成的时空网络与生态机制(项目编号7242244)
(二)发表论文
1. Huihui Zhang, Xinke Zhang, Guoshuai Zhang, Xiao Sun, Shilin Chen, Linfang Huang*. Assessing the quality ecology of endemic tree species in China based on machine learning models and UPLC methods: The example of Eucommia ulmoides Oliv. Journal of Cleaner Production, 452 (2024) 142021.
2. Yan, Q., Zhang, X., Li, M., Zhang, G., & Huang, L.-F*. (2024). Global climate change promotes aboveground growth and high-latitude species distribution in medicinal plants: Insights from the genus Panax. Journal of Cleaner Production, 143863. [DOI](https://doi.org/10.1016/j.jclepro.2024.143863).
3. Xinke Zhang, Guoshuai Zhang, Qi Yan, Bashir Ahmad, Jin Pei*, Linfang Huang*. Quality variation and salt-alkali-tolerance mechanism of Cynomorium songaricum: Interacting from microbiome-transcriptome-metabolome. Science of the Total Environment, 919 (2024) 170801.
4. Lixia Tian, Ranran Gao, Yuxiang Cai, Junxian Chen, Hongmei Dong, Shanshan Chen, Zaichang Yang, Yu Wang*, Linfang Huang* and Zhichao Xu*. A systematic review of ginsenoside biosynthesis, spatiotemporal distribution, and response to biotic and abiotic factors in American ginseng. Food & Function, 2024, 15(5): 2343-2365. [DOI](https://doi.org/10.1039/D3FO03434H).
5. Xinke Zhang, Guoshuai Zhang, Lixia Tian, Linfang Huang*.Ecological regulation network of quality in American Ginseng: Insights from macroscopic-mesoscopic-microscopic perspectives. Industrial Crops and Products, 2023, 206: 117617.
6. Tiexin Zeng, Qi Xiao, Jianuo Zhang, Xiao Sun, Baolin Guo, Jin Pei* and Lin-Fang Huang*.Identification of a secondary Q-marker in high-quality ecotypes of Carthamus tinctorius L. and exploration of the target preference. Food & Function, 2023, 14, 2710-2726. [DOI](https://doi.org/10.1039/D2FO02596E).
7. Miao Yujing, Zhang Xinke, Pei Jin, Liu Chang, Huang Linfang*.Adaptive bacterial and fungal matching between a parasitic plant and its host: A case of Cistanche deserticola and Haloxylon ammodendron. Industrial Crops and Products, 2023, 191: 115932.
8. Sun Xiao, Pei Jin, Lin Yulin, Li Baoli, Zhang Li, Ahmad Bashir, Huang LinFang*.Revealing the Impact of the Environment on Cistanche salsa: From Global Ecological Regionalization to Soil Microbial Community Characteristics. Journal of Agricultural and Food Chemistry, 2020, 12;68(32):8720-8731.
9. Xinke Zhang, Guoshuai Zhang, Yujing Miao, Xiao Sun, Linfang Huang*.Effects of different drying methods on physico-chemical properties, bioactive and taste substances of Cynomorium songaricum. LWT - Food Science and Technology, 2023, 185: 115159.
10. Yan Zheng, Xiao Sun, Yujing Miao, Shunwang Qin, Yuan Jiang, Xiang Zhang, Linfang Huang*.A systematic study on the chemical diversity and efficacy of inflorescence and succulent stem of Cynomorium songaricum. Food & Function, 2021, 12, 7501–7513.
11. Tiexin Zeng, Xiao Sun, Yujing Miao, Shengjiu Gu, Lixia Tian, Yan Zheng, Yuan Jiang, Xinke Zhang, Zhan Feng, Jin Pei*, Linfang Huang*.Integrating bioclimatic factors and secondary metabolism to predict the suitable producing area of plants with high specific metabolite content in a real-world environment - a case of Carthamus tinctorius L. Industrial Crops & Products, 177 (2022) 114545.
12. Sun X, Zhang X, Zhang G, Miao Y, Zeng T, Zhang M, Zhang H, Zhang L, Huang L*.Environmental Response to Root Secondary Metabolite Accumulation in Paeonia lactiflora: Insights from Rhizosphere Metabolism and Root-Associated Microbial Communities. Microbiology Spectrum, 2022 Dec 21;10(6):e0280022.
13. Lizhi Wang, Zhen Wang, Weiwei Gao, Juan Chen, Meihua Yang, Ying Kuang, Linfang Huang*, Shilin Chen*.Simultaneous determination of a?atoxin B1 and ochratoxin A in licorice roots and fritillaria bulbs by Solid-phase extraction and high performance liquid chromatography with tandem mass spectrometry. Food Chemistry, 138:1048-1054,2013.
14. Duan Baozhong, Huang Linfang*, Chen Shilin*.Study on the destructive effect to inherent quality of Fritillaria thunbergii Miq. (Zhebeimu) by sulfur-fumigated process using chromatographic fingerprinting analysis. Phytomedicine, 2012, 19(6):562-8.
(三)论著
1.《中国药用植物叶绿体基因组图谱(第二册)》主编,科学出版社,2023
2.《中国药用植物叶绿体基因组图谱(第一册)》主编,科学出版社,2020
3.《中国土家族常用药物图谱》 主编,军事医学科学出版社, 2016
4.《中国药材产地生态适宜性区划》副主编,科学出版社,2017
5.《常见药用植物快速识别》副主编,中国林业出版社, 2017
6.《常用中药材及饮片快速识别》副主编,中国林业出版社, 2015
(四)获奖
1.“基于高分辨UPLC-MSn及分子网络数据分析技术的民族药新药发现及应用”获2018年中国中西医结合学会科学技术奖二等奖(排名第一)
2.“内蒙古产道地药材黄芪的规范化生产与资源利用”获2016年中华中医药学会科学技术三等奖(排名第一)
3.“西南高半山民族地区道地民族药物规范化生产与开发利用”获2017年中国民族医药学会科学技术奖二等奖(排名第二)
4.“对川贝母新基原太白贝母列入《中国药典》的研究与应用”获2014年广东省科技二等奖(排名第八)
5. “对川贝母新基原太白贝母的研究与应用”获2013年广州市科技进步二等奖 (排名第八)