杨倩倩
一、个人简介
杨倩倩,副教授,中共党员,必赢体育app下载,必赢体育中药学博士后,四川大学药物化学博士(2+3直博),硕士研究生导师,Chinese Chemistry Letters青年编委,中国中药协会真实世界研究专委会委员。主要从事中药药效物质来源、成药性与制造问题开展中药药效物质作用机制、药效物质后修饰与绿色制造研究;主讲本科生《有机化学》、《有机化学实验》等课程;主持/参与国家自然科学基金等各级项目6项;以第一作者或通讯作者在Angew. Chem., Int. Ed.、Med. Res. Rev、ACS Catal.、Chin. Chem. Lett.、Research、Org. Chem. Front.、Org. Lett.、Chem. Commun.等期刊发表学术论文15篇,包括封面论文2篇。主持教改项目1项,发表教改文章2篇。
二、代表性成果(可含承担项目、发表论文、论著、获奖等)
(一)承担项目
1. 国家自然科学基金青年科学基金项目(C类),22401025,30万,主持
2. 必赢体育app下载,必赢体育杏林学者博士后专项,BSH2021022,12万,主持
3. 国家自然科学基金委员会面上项目, 82374155,49万元, 参与
4. 国家自然科学基金委员会, 重点项目, 21931006, 300万元, 参与
(2)发表论文
1.Ze-Hong Zheng, Mu-Qiu Chen, Jin Zhou, Jie Wang, Yan-Rong Wei, Cheng Peng, Gu Zhan, Qian-Qian Yang*, Bo Han*, Diverse synthesis of bridged bicyclo[3.2.1]octa-2,6-diene and tricyclo[3.2.1.0?,7] oct-3-ene frameworks via stepwise cascade reactions. Chin. Chem. Lett. 2025. 10.1016/j.cclet.2025.111202.
2.Qian-Qian Yang, Chen Chen, Dahong Yao, Wei Liu, Bo Liu, Jin Zhou, Dabo Pan, Cheng Peng, Gu Zhan*, Bo Han*, Catalytic Atroposelective Synthesis of Axially Chiral Azomethine Imines and Neuroprotective Activity Evaluation,Angew. Chem. Int. Ed. 2024, e202312663.
3.Shuai-Jiang Liu, Qian Zhao, Xiao-Chen Liu, Allan B. Gamble, Wei Huang, Qian-Qian Yang*, and Bo Han*, Bioactive atropisomers: Unraveling design strategies and synthetic routes for drug discovery, Med. Res. Rev. 2024, 10.1002/med.22037.
4.Qian-Qian Yang, Shuai-Jiang Liu, Wei Huang, Cheng Peng, and Bo Han*, Exploring Protein Bioconjugation: A Redox-Based Strategy for Tryptophan Targeting, Research, 2024, 10.34133/research.0410.
5.Qian-Qian Yang, Ze-Hong Zheng, Meng Wang, Jin Zhou, Cheng Peng, Wei Du, Gu Zhan, and Bo Han*, Ag-Catalyzed Switchable Synthesis of Site-Specifically Functionalized Pyrroles via Azafulvenium Intermediates, Org. Lett. 2024, 10.1021/acs.orglett.4c01437.
6.Jin Zhou, Chen Chen, Qiwen Pang, Wei-Fang Zuo, Xiang Li, Gu Zhan, Qian-Qian Yang*, and Bo Han*, Cooperative photoactivation/Lewis base catalyzed [4+2] annulations of α-diazoketones and ortho-amino MBH carbonates to access dihydroquinolinone frameworks. Org. Chem. Front. 2023, 10, 1034-1041.
7.Ben-Hong Chen, Shuai-Jiang Liu, Qian Zhao, Qiumeng Hou, Jia-Li Yuan, Gu Zhan, Qian-Qian Yang*, and Wei Huang*, Palladium-catalyzed asymmetric [4+2] annulation of vinyl benzoxazinanones with pyrazolone 4,5-diones to access spirobenzoxazine frameworks, Chemical Communications, 2023, 59, 1233-1236.
8.Wei-Fang Zuo, Yang Zhang, Yulin Luo, Xiang Li, Gu Zhan, Jin Zhou, Qiwen Pang, Qian-Qian Yang*, and Bo Han*, Visible-light-mediated substituent-controlled regiodivergent (2 + 2)/(3 + 2) cycloadditions for the synthesis of aza-analogs of β-lactam and γ-fused lactam derivatives, Org. Chem. Front. 2024, 10.1039/D4QO00584H.
9.Meng Wang, Ze-Hong Zheng, Mu-Qiu Chen, Gu Zhan, Jie Wang, Qian-Qian Yang*, Wei Huang*, An umpolung strategy for chemoselective metal-free [4 + 2] annulation of azlactones: access to tetrahydro-β-carbolin 1,3-diketone frameworks. Org. Chem. Front. 2024, 11, 822-829.
10.Jing Xue, Meng Wang, Qian Zhao, You-Cheng Wang, Qian-Qian Yang*, Bo Han* Asymmetric Synthesis of Tricycle-Fused Dispirooxindoles via Organocatalyzed Three-Component Cascade Reactions of 2-Pyrones and Trifluoroethylisatin Ketimines. Adv. Syn. Cat. 2022, 364, 3888.
11.Wu-Jingyun Zhou, Xiaoning Yu, Chen Chen, Wei Lan, Gu Zhan, Jin Zhou, Qian Liu, Wei Huang*, Qian-Qian Yang*, Organocatalytic Asymmetric [4 + 2] Cyclization of Azadienes with Azlactones: Access to Chiral 3-Amino-δ-Lactams Derivatives. J. Org. Chem. 2023, 88, 13427-13439.