周勤梅
一、个人简介:
周勤梅,博士学历、高级实验师、硕士生导师、必赢体育app下载,必赢体育药学院。主要从事中药药性理论和药效物质基础研究。主持国家自然科学基金(广藿香“芳香”倍半萜治疗“湿浊带下”霉菌性阴道炎的药效物质与作用机制)、四川省自然科学基金(基于Ca2+/CaMKⅡ/CREB/BDNF信号通路研究“芳香化湿”药广藿香“醒脾解郁”的效应物质和作用机制)等各级项目5项;主研国家自然基金重点项目、国家自然基金面上项目、四川省杰出青年基金等项目。共发表学术论文40余篇,其中,以第一作者或通讯作者发表SCI论文8篇、北大中文核心期刊论文10余篇,出版著作1部,获得授权发明专利7项。
二、代表性成果(可含承担项目、发表论文、论著、获奖等)
发表论文(#为第一作者,*为通讯作者):
1. Qin-Mei Zhou#, Hao-Yu Zhao#, Chuan Ma#, Lu Huang, Jie Liu, Li Guo, Cheng Peng*, Liang Xiong*. Pocahemiketone A, a sesquiterpenoid possessing a spirocyclic skeleton with a hemiketal endoperoxide unit, alleviates Aβ25-35-induced proptosis and oxidative stress in SH-SY5Y cells[J]. Organic Letters, 2022, 24, 4734-4738.
2. Lu Huang, Cheng Peng*, Li Guo, Rui Feng, Hong-Zhen Shu, Yun-Cai Tian, Qin-Mei Zhou*, Liang Xiong*. Six pairs of enantiomeric phthalide dimers from the rhizomes of Ligusticum chuanxiong and their absolute configurations and anti-inflammatory activities[J]. Bioorganic Chemistry, 2022, 127: 105970.
3. Jing Zuo#, Tian-Hao Zhang#, Liang Xiong, Lu Huang, Cheng Peng, Qin-Mei Zhou*, Ou Dai*. Two pairs of 7,7′-cyclolignan enantiomers with anti-inflammatory activities from Perilla frutescens[J]. Molecules, 2022, 27: 6102.
4. Hao‐Yu Zhao#, Qin‐Mei Zhou#, Huan Zhu, Fei Zhou, Chun‐Wang Meng, Hong‐Zhen Shu, Zhao‐Hua Liu, Cheng Peng*, Liang Xiong*. Anisotanols A–D, four norsesquiterpenoids with an unprecedented sesquiterpenoid skeleton from Anisodus tanguticus[J]. Chinese Journal of Chemistry, 2021, 39: 3375-3380
5. Fei Zhou#, Ou Dai#, Cheng Peng*, Liang Xiong, Hui Ao, Fei Liu, Qin-Mei Zhou*. Pro-angiogenic effects of essential oil from Perilla frutescens and its main component (Perillaldehyde) on zebrafsh embryos and human umbilical vein endothelial cells[J]. Drug Design, Development and Therapy, 2021, 15: 4985-4999.
6. Xiao-Ya Wang#, Qin-Mei Zhou#, Li Guo, Ou Dai, Chun-Wang Meng, Lu-Lin Miao, Jie Liu, Qiao Lin, Cheng Peng*, Liang Xiong*. Cardioprotective effects and concentration-response relationship of aminoalcohol-diterpenoid alkaloids from Aconitum carmichaelii[J]. Fitoterapia, 2021, 149: 104822.
7. Qin-Mei Zhou#, Ming-Hua Chen#, Xiao-Hong Li, Cheng Peng*, Da-Sheng Lin, Xiao-Nian Li, Yang He, Liang Xiong*. Absolute Configurations and Bioactivities of Guaiane-Type Sesquiterpenoids Isolated from Pogostemon cablin[J]. Journal of Natural Products, 2018, 81(9): 1919-1927.
8. Huan Zhu#, Qin-Mei Zhou#, Cheng Peng*, Ming-Hua Chen, Xiao-Nian Li, Da-Sheng Lin, Liang Xiong*. Pocahemiketals A and B, two new hemiketals with unprecedented sesquiterpenoid skeletons from Pogostemon cablin[J]. Fitoterapia, 2017, 120: 67-71.